Sam Crossman

Sam

I grew up in the New Forest on the south coast of England and completed my undergraduate degree in Biochemistry at the University of Sussex in 2013. During my time in Sussex, I was lucky enough to complete a Biochemical Society funded summer studentship in the lab of Dr. Sarah Newbury at Brighton and Sussex Medical School. It was during this time that my interest inĀ developmental biology first developed.

My current work as a PhD student in the Vincent lab aims to uncover some of the mechanisms employed by Drosophila to rid its tissues of potentially harmful cells. One way of doing this is through apoptosis, a controlled form of cell death. Whilst a number of harmful stimuli are known to be capable of triggering apoptosis, I am particularly interested in the death that occurs in the embryonic epidermis upon the removal of genes responsible for patterning the major body axis. It has been previously hypothesised that these cells die because they lack the required patterning information to contribute productively towards a developing organism and attempting to understand this process forms the basis of my research.

ftz dcp1

Cleaved caspase staining (green) of a embryo mutant for the pair rule gene fushi tarazu (ftz) to visualise dying cells. The segment marker, engrailed, is shown in red.

Outside of the lab my time is spent keeping active (I enjoy football and running) and supporting Southampton FC. I try to make it to as many games as the time and monetary constraints of graduate study will permit!

SexLethal2014-6

In action for the lab football team, Sex Lethal FC.

Email: Sam.Crossman@crick.ac.uk,

Twitter: @shcrossman